IV Doses of Vitamin C Show Promise in Cancer
This just in from Patrick Holford. Patrick is an
acknowledged expert who is always looking for natural
You always knew that vitamin C was essential but this new
study is putting a whole new view to how important that little
High-dose vitamin C can be effective against cancer,
according to research published this week in the Proceedings of
the National Academy of Sciences.1
In a comprehensive study, Dr. Qi Chen
and colleagues at the National Institutes of Health (NIH)
showed that high doses of vitamin C caused cell death across a
wide range of cancer cell lines--including lymphoma, melanoma,
and cancers of the breast, lung, colon, and kidney. The
concentrations of vitamin C used in the study could be achieved
only by intravenous (IV) administration, not by taking it
The high-dose vitamin C led to the formation of hydrogen
peroxide, a chemical that can kill cancer cells. The effects
were seen in both animal and human cancer cell lines. Normal
cells were not affected by the vitamin C at any
This research reinforces studies conducted in the 1970s by
Nobel Prize winner Dr. Linus Pauling. In Pauling's research, he
gave 100 terminally ill cancer patients 10 grams (10,000
milligrams) of vitamin C each day. He compared their outcomes
with 1,000 cancer patients given conventional therapy. The
survival rate was five times higher in those given vitamin C.
In addition, 13 patients in the vitamin C group were still
alive 10 years later, with 12 apparently free of cancer, while
all of the patients in the control group died.2
At the time, however, Pauling's findings were discredited.
This was largely due to an apparent "replication" of the study
by the Mayo Clinic that showed no benefit from vitamin
C.3 But there were two major differences between the
Pauling trial and the study by the Mayo Clinic. The terminally
ill patients in the Pauling trial kept taking vitamin C every
day, while those in the Mayo Clinic trial stopped after an
average of 75 days. Also, patients in Pauling's study were
given a combination of oral and IV vitamin C. In the Mayo
Clinic study, only oral vitamin C was used.
Other studies have confirmed Pauling's results. In the
1980s, Drs. Murata and Morishige of Saga University in Japan
showed that cancer patients taking 5-30 grams of vitamin C
lived six times longer than those taking 4 grams or less. Those
suffering from cancer of the uterus lived 15 times longer on
vitamin C therapy.4
Research has also shown a role for vitamin C in cancer
prevention, and a high dietary intake is associated with
lower risk for several cancers.
In a 1991 review of prevention studies,5 Dr.
Gladys Block, formerly with the National Cancer Institute
(NCI), concludes, "Approximately 90 epidemiologic studies have
examined the role of vitamin C or vitamin C-rich foods in
cancer prevention, and the vast majority have found
statistically significant protective effects. Evidence is
strong for cancers of the esophagus, oral cavity, stomach, and
pancreas. There is also substantial evidence of a protective
effect in cancers of the cervix, rectum, and breast. Even in
lung cancer...there is recent evidence of a role for vitamin
The Bottom Line
There is strong evidence that intravenous (IV) vitamin C can
be an effective, non-toxic, and inexpensive form of cancer
therapy. My advice for cancer patients is to find a doctor who
can administer IV vitamin C. You can contact the American
College for Advancement in Medicine (ACAM) at 888-439-6891 for
To reduce your risk of cancer, I recommend eating at least
five servings of fruits and vegetables each day. The best
choices for vitamin C are broccoli, peppers, berries, and
citrus fruit. I also recommend supplementing 1,000 mg of
vitamin C twice a day.
Wishing you the best of health,
1 Chen, Q, Espey, MG, Krishna, MC, Mitchell, JB,
Corpe, CP, Buettner, GR, Shacter, E, and Levine, M. 2005.
Proc Natl Acad Sci 102(38): 13604-13609.
2 Cameron, E, and Pauling, L. 1976. Proc Natl
Acad Sci 73(10): 3685-3689; Cameron, E, and Pauling, L.
1978. Proc Natl Acad Sci 75(9): 4538-4542; Jaffey, M.
1982. Med Hypothesis 8(1): 49-84.
3 Creagan, ET. 1979. N Engl J Med 301:
4 Murata, A, and Morishige, F. 1981. International
Conference on Nutrition, Taijin, China.
5 Block, G. 1991. Am J Clin Nutr 54: